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And then we can't operate on people who are smoking

This has occurred in some of my patients, where the drug has no effect, he continues

We conducted a comprehensive literature search across databases, including PubMed and Web of Science, compiling data from clinical trials, case reports, and basic research studies published up to 2025, with a focus on the efficacy, safety, and mechanism of action of drugs such as liraglutide, semaglutide, and tirzepatide in patients with MC4R deficiency

While the term specifically refers to Ozempic, it broadly encompasses all GLP-1 medications

In the new study, which has not yet been published in a peer-reviewed journal, researchers analyzed five years of medical records from more than 146,000 adults with a diagnosis of both obesity and Type 2 diabetes