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In this study, we noted that the strongest alterations in glutathione metabolism were in the liver, potentially because hepatic glutathione is produced at much higher concentrations (10 mM), whereas intracellular glutathione concentrations are approximately 12 mM [31]

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Nevertheless, because of the large population heterogeneity among the few published prospective studies, the reason for the apparent variation in results is unknown

Pediatr Nephrol 41 , 663673 (2026)

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