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All subjects treated with ALCAR were concomitantly treated with riluzole, while about 7% of those not treated with ALCAR did not take riluzole
274,275 Therapeutic strategies targeting oxidative stress and mitochondrial dysfunction include using antioxidants like alpha-lipoic acid (ALA), which improves neuropathic symptoms and nerve conduction velocities in patients with DPN
doi:10.1016/0014-5793(88)80509-x Simeon A, Monier F, Emonard H, et al
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