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In this part of the trial, as expected, brodalumab showed the most benefit in the ACR20 of those previously on placebo

5-Amino-1MQ Vials (50 mg each): 1 week (5 mg/day) 1 vial 2 weeks (5 mg/day) 1 vial 4 weeks (5 mg/day) 2 vials Insulin Syringes (U-100): Per week (once daily): 7 syringes Per week (BID): 14 syringes 4 weeks (once daily): 28 syringes Bacteriostatic Water (10 mL bottles): Use 4.0 mL per vial for reconstitution

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Because of the 0.9% benzyl alcohol, bacterial growth is inhibited , so the opened vial remains sterile for multiple transfers (usually up to ~28 days if kept sealed and refrigerated)

doi: 10.1016/j.ghir.2020.101319 71 SnyderDKClemmonsDRUnderwoodLE