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Expanding applications of therapies based on GLP1

Experimental evidence has demonstrated that the activation of medial amygdala-ventromedial hypothalamic circuits under acute stress drives behavioral adaptations while concurrently modulating glucose homeostasis

514 Obesity of PWS subjects shows distinct phenotypic and metabolic characteristics that are not common to simple obesity

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Behavioural interventions : Structured programmes addressing eating behaviours, psychological factors, and sustainable habit formation demonstrate superior long-term outcomes compared to medication alone