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PLoS ONE 14(12):e0227271

Naunyn-Schmiedebergs Arch Pharmacol 397(4):19851995 Al-Ozairi E, Alsaeed D, Alroudhan D, Voase N, Hasan A, Gill JMR, Sattar N, Welsh P, Gray CM, Boonpor J, Celis-Morales C, Gray SR (2021) Skeletal muscle and metabolic health: how do we increase muscle mass and function in people with type 2 diabetes

Down-regulation of inducible nitric oxide synthase (iNOS) in AD-model mice, and subsequent decrease in NO, has been associated with rescue of cognitive function, reduction in Ab and NFT load, decreased glial activation, and attenuated neuronal loss [9-11]

This origin is what places MOTS-c in a separate research category from hGH-fragment or GHRH-analog compounds, since its activity is rooted in mitochondrial biology rather than the pituitary-hormone axis

Blood Lipid and Blood Pressure Stability The mean changes from baseline in HDL and LDL were smaller and non-significant at 12 months