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There is a very short study on Methionine restriction involving a small sample size of human patients

Do not freeze reconstituted solutions

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it can be taken as a pill or under the tongueis when there is a deficiency that can be caused by pernicious anemia, celiac or Crohns disease, or weight loss procedures such as gastric bypass surgery, which interferes with the bodys ability to extract vitamins from food

For weight loss specifically, this is not a close comparison