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Overweight and obese patients lost an average of 15-20% of their body weight (34 to 48 lbs.) over 72 weeks compared to a 3% loss in participants who were given a placebo injection

Cyclooxygenase-2 (COX-2) is a key regulatory molecule that catalyzes the synthesis of arachidonic acid to prostaglandin (PG), which is expressed in large quantities when cells are stimulated by inflammation, accelerating the occurrence of inflammatory storms (105)

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