Shi, G., et al., Ptrf transgenic mice exhibit obesity and fatty liver
These carotenoids preferentially accumulate in the retina, enhance macular pigment density, and protect against age-related macular degeneration (23)
This establishes a vicious cycle of diminished carnitine uptake and accelerated urinary loss, further disrupting energy metabolism(Fig
1 , 9 The mortality rate is higher in patients with PWS than within the general population, and prognosis is significantly conditioned by proactive interventions to prevent morbid weight excess
Single-stranded DNA antibodies have also been identified (505), along with anti-ganglioside antibodies (508), autoantibodies against endothelial and neuronal cells (506), and phospholipid autoantibodies (506, 508, 509)