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Nat Methods 12, 78, doi: 10.1038/nmeth.3213 (2015)
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Their work reveals the role of a transporter protein named SLC33A1 in shuttling oxidized glutathione (GSSG) across the ER membrane, a process vital for sustaining the oxidative environment necessary for correct protein folding
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In vitro and in vivo animal studies have explored how peptide-based interventions can modulate these pathways, with research demonstrating peptide-mediated suppression of UV-induced MMP expression and reduction in oxidative stress markers in irradiated cell cultures
