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This study had several limitations to consider, including a small sample size and a relatively short follow-up period, both potentially influencing the studys ability to derive substantial statistical findings

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Compared to placebo, the treatment with intramuscular acetyl-l-carnitine significantly reduced weekly mean pain on the VAS, whilst during the open-label part of the study, oral acetyl-l-carnitine improved symptoms in the entire cohort, with no safety issues [81] (Table 2)