Cisplatin nephrotoxicity leads to decreased creatinine clearance, increased serum creatinine levels, increased urea levels, increased urine output, and decreased glomerular filtration rate [100,101]
Regarding AR-V7, its expression was increased in the xentuzumab + enzalutamide group compared with the enzalutamide-only group (Weyer-Czernilofsky et al., 2020)
Gastroparesis When the stomach is working properly, spontaneous muscle contractions in the stomach cause movement of materials in the stomach, which leads the stomach to empty
Both are generally considered safe for most healthy adults
Enter Retatrutide Retatrutide is the first triple agonist targeting 3 metabolic receptors at once: GLP-1: Enhances insulin, reduces appetite, slows digestion GIP: Boosts insulin, improves lipid metabolism GCGR: Increases energy expenditure, burns fat GLP-1 activation stimulates insulin secretion from pancreatic -cells, reduces appetite through central pathways, and slows gastric emptying to reduce glucose spikes
