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One notable advantage of our assay is that it enables accurate measurements of GPx activity, even when working with low substrate concentrations

Mice in the DMM + ferroastatin-1 and DMM + rhosin groups received intraperitoneal ferroastatin-1 (15 mg/kg) and rhosin (40 mg/kg), respectively, twice/week (21,22), while mice in the control and DMM groups were administered an equivalent volume of normal saline on the same schedule

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In addition to catalyzing this major CoQ 10 -reducing reaction, complex I pumps protons into the intermembrane space, generating a proton motive force that drives ATP synthesis 68,70

Storage & Stability: Lyophilized powders are short-term and stable at room temperature for several weeks