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If you have a history of thyroid cancer, pancreatitis, severe diabetic retinopathy, or are pregnant, certain GLP-1 options may be restricted

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Among them, the cytosolic enzyme nicotinamide N-methyltransferase (NNMT) has been newly discovered to regulate the levels of nicotinamide precursors required for NAD+ biosynthesis, and therefore plays a crucial role in regulating the NAD+ salvage pathway and cellular metabolism