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Pharma companies are running what marketers call disease-awareness ads, which explain the ailment a given medicine treats but stop short of actually mentioning the drug itself, sparing actors from having to recite mood-killing side effects whose mention might otherwise also give viewers pause
In the livers of ALC-treated mice, cholesterol metabolism-related genes exhibited changes, with significant decreases in SREBP2 and HMGCR, key components of the cholesterol synthesis pathway
doi: 10.1038/nature11986 16 MondanelliGIaconoAAllegrucciMPuccettiPGrohmannU
Gradual Increase : After two to four weeks, if well-tolerated, the frequency of application can be gradually increased to nightly use
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