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These side effects often improve over time and can be managed with gradual dose increases, eating bland foods, and staying well-hydrated

Acknowledgments This work was supported by Alibaba Cloud

For instance, some individuals think they will stop taking them once theyve lost weight while others are only using them cosmetically and not for management of a chronic disease. Call for more research In a new JAMA Viewpoint opinion piece, Khan and others call for more research to understand the causes of this discontinuation and the development of clinical and policy interventions to support long-term use

If you want maximum flexibility and the longest possible shelf life before starting your protocol, lyophilized is the clear winner

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