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DOI: 10.1080/15563650.2019.1606432 Aroda VR et al, "Long-term metformin use and vitamin B12 deficiency in the Diabetes Prevention Program Outcomes Study." Journal of Clinical Endocrinology and Metabolism, Feb

Possible Side Effects Vitamin B12 injections are generally very safe

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If severe B12 deficiency with neurological involvement is suspected, treatment should be initiated promptly without waiting for test results, and specialist advice may be needed