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A large determinant of this adaptability is experience-driven neuronal activity, which has been shown to promote myelination and contribute to the modification of established myelin sheaths (Wake et al., 2011

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Animal studies have demonstrated that GLP-1 RAs reduce the self-administration of alcohol, opioid, nicotine, and cocaine effects [that] are believed to be mediated through interactions with the mesolimbic dopamine system, the researchers wrote

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