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For longer-term storage, freezing is standard practice for lyophilized peptides

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STEP 1 extension trial (Wilding et al., NEJM 2022)

One patient I spoke to had been using compounded GLP-1s to manage her lupus symptoms because of cost issues and was increasing her dose without consulting her doctor whenever she felt its effects plateau

For patients with COMISA (comorbid insomnia and sleep apnea), some studies have shown that starting CBT-I before beginning positive airway pressure (PAP) therapy leads to better PAP adherence and greater improvement in insomnia symptoms compared to starting PAP without prior CBT-I 4,5