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George JF, Braun A, Brusko TM, Joseph R, Bolisetty S, Wasserfall CH, et al

The resulting oxidized form of GSH either reacts with another GSH molecule to form GSSG or with cysteine groups on cellular proteins to form protein GSH mixed disulfides, a process known as protein glutathionylation. This latter reaction can change the proteins structure and function, which can, in turn, evoke a functional change within the cell

The frequency of injections depends on individual needs and medical advice, but many people receive injections once a week if they are deficient

Nat Commun 12:6235