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Disruption of oligodendrocyte progenitor cells is an early sign of pathology in the triple transgenic mouse model of Alzheimers disease

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Failure of this response, which is dependent on TLR9 signaling from plasmacytoid dendritic cells (pDC) was observed in homozygous mutants, and subsequently, failure of TLR7 (but not TLR3) signaling was observed as well

doi: 10.1111/and.13953 82 WongWYMerkusHMThomasCMMenkveldRZielhuisGASteegers-TheunissenRP

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