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Oxidative stress induces ferroptotic cell death in retinal pigment epithelial cells

In one clinical trial, PNS shows renoprotective effects on reducing albuminuria, proteinuria and Scr in patients with DKD (Tang et al., 2020)

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However, it is essential to note that GSH levels in both dose groups generally returned to baseline levels after a one-month washout period, suggesting that continuous supplementation is necessary to maintain elevated GSH levels

Some individuals tolerate GHK-CU well at half the standard dose but experience problems at full doses