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The family of proteins, peroxiredoxins (Prxs) can catalyze the reduction of H 2 O 2 in the presence of GSH and/or other thiols

Indeed, U24 and U25 are among the most strongly cat2 -induced genes on a fold-change basis (Queval et al., cat2 and cat2 gr1 (Figure 4, compare A and B with C and D)

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Weight reduction and improved insulin sensitivity may lower inflammatory signaling