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FORMULA: INDICATIONS: In the treatment of vitamin B12 deficiency states (avitaminosis and hypovitaminosis), which are associated with macrocytic anemias and anemias produced after hemorrhage and surgical acts

Long-term safety is completely unknown

Current guidelines recommend alpha-2-delta calcium channel ligands (gabapentin, pregabalin, or FDA-approved gabapentin enacarbil) as first-line pharmacological treatment

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Future studies could help clarify which specific subgroups of patients benefited the most from GLP-1RAs, whether this would be based on the baseline BMI, metabolic health or duration of therapy