Endocrinologia, Diabetes y Nutricion, 64 (5), 278280
Garzon, R., Marcucci, G
Moreover, clinical studies have indicated that NPS, especially depression, are risk factors for cognitive decline and more rapid progression of the disease (Umucu et al., 2019
The two most effective bariatric procedures, Roux-en-Y gastric bypass (RYGB) and vertical sleeve gastrectomy (VSG) both result in enhanced meal-stimulated GLP-1 release which may be contributing to improvements in glucose metabolism and weight loss induced by these procedures
In this context, the glucagon-like peptide-1 (GLP-1) receptor system has emerged as a paradigm-shifting model ( 3 GLP-1 receptor signaling and GLP-1RA in metabolic disorders The global prevalence of metabolic dysfunction, encompassing obesity and T2DM, has reached pandemic proportions (Rohm et al., 2022), and organelle dysfunction (Lemmer et al., 2021)