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These approaches typically involve: Lower maintenance doses (200-300mcg daily) Monthly assessment checkpoints Flexible adjustment windows Extended rest periods (4-6 weeks minimum) Research Note: Extended protocols should only be undertaken with comprehensive monitoring and documentation

While dietary supplements are less tightly regulated than drugs, the FDA still requires them to only contain ingredients found on a list of approved substances

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The findings will need to be replicated in the general population, although Corley was enthusiastic about the translational potential