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Rapid weight loss without resistance training causes significant muscle loss along with fat loss

The amount of weight lost varies between individuals, but studies have shown significant weight loss in participants using Ozempic combined with lifestyle interventions like diet and exercise

They established that the drug had caused non-arteritic anterior ischaemic optic neuropathy (Naion), a condition that reduces blood flow to the optic nerve, potentially leading to permanent vision loss

Nature 572 , 347351 (2019)

As a pan-ERR agonist with strongest activity at ERR, it enables mechanistic dissection of receptor-coactivator circuits that couple mitochondrial function to organismal energetics