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Another independent study showed that extra virgin olive oil (EVOO) in a mouse model of SLE significantly up-regulated the expression of NRF-2 and HO-1 proteins and effectively ameliorated the activation status of JAK/STAT, MAPK, and NF-B pathways (241)

A recent systematic review and meta-analysis of 21 randomized, placebo-controlled trials examining the effect of B-vitamin supplementation found the supplementation decreased homocysteine concentrations and improved measures global cognitive function but had no effect on individual measures of executive function, information processing speed, or episodic memory (89)

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doi: 10.1016/j.ejmech.2020.112193 195 TsilimigrasD