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Clinical evidence confirms these benefits, with nano-curcumin demonstrating significant improvements in both neuropathy scores (Toronto Clinical Scale) and metabolic parameters (fasting glucose, HbA1c) in T2DM patients [215]

doi: 10.1158/1541-7786.MCR-11-0156

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Restoration of rab1 levels prevents endoplasmic reticulum stress in hippocampal cells during protein aggregation triggered by rotenone

There is no single best compound, because each targets a different hallmark of aging