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While focusing on the HDAC inhibitory effects of butyrate, we further systematically summarize the regulatory role of its metabolic intermediates on PTMs, which provides a comprehensive indirect mechanism for revealing the biological functions of butyrate (Table 1)

Angiogenesis and Blood Supply A 2025 systematic review of BPC-157 in orthopaedic sports medicine found consistent preclinical evidence that the peptide activates VEGFR2-linked angiogenic signalling at injury sites Vasireddi et al

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The effect of ageing on the response to frusemide in normal subjects

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