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The primary endpoint was to demonstrate that orforglipron is superior to placebo in the maintenance of body weight reduction in participants who achieved plateau with either Zepbound or Wegovy in the SURMOUNT-5 trial

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Omega-3 Fatty Acids Omega-3 fatty acids specifically EPA and DHA have been studied in the context of muscle protein synthesis and inflammation management during caloric restriction

To lessen renal injury, SalB enhances the nuclear accumulation of Nrf2 and suppresses NLRP3 activation, oxidative stress, and Caspase-1/Gasdermin D-mediated cellular pyroptosis via the Nrf2/NLRP3 pathway (Pang et al., 2020)

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