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For example, a meta-analysis of 31 randomized, controlled trials reports that the most common side effects observed in the hGH studies and their respective incidences were [16]: Soft tissue edema: 50% Insulin resistance: 22% Arthralgias: 21% Carpal tunnel syndrome: 19% These side effects are transient and usually subside as the patient gets used to the therapy

Cathepsin B was also associated with autoimmune disorders and osteoporosis, suggesting that a better understanding of this protein and its inhibitors could improve the treatment of several disorders that lack specific therapies (Toomey et al., 2014

H., Gopalakrishnan, G., Hennessey, J

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