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The importance of Nrf2-induced xCT activity and persulfidation of cysteine residues to inhibit inflammasome activity was recently confirmed in a study which directly demonstrated persulfidation of NLRP3 cysteine residues [115]

The effects of L-carnitine supplementation on indicators of inflammation and oxidative stress: A systematic review and meta-analysis of randomized controlled trials

Astrocytes in ALS show many signs of functional decline, for example they demonstrate abnormal Ca 2+ signalling, 573 impaired secretion of neuroprotective glial-derived neurotrophic factor, 574 as well as reduced lactate production