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Trazodone proves efficacious for insomnia due to its elevated propensity for inducing somnolence compared to second-generation antidepressants, such as mirtazapine (42% versus 25%)

Mice demonstrating severe distress signs at the end of the experiment were humanely euthanized via CO2 inhalation, followed by cervical dislocation

Frontiers in bioscience

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excluded participants demonstrates that the excluded group is generally comparable to the included group in terms of sociodemographic and health-related factors (Table S1)