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778, 2018, pp

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Ipamorelin works through a different receptor (GHS-R1a, the ghrelin receptor) and is selective: it does not materially raise cortisol, prolactin, or aldosterone in research models

Multicenter series indicate that 7080% of genetically confirmed patients improve or stabilize on 1060 mg kg 1 day 1 , with greater benefit when therapy starts within 12 months of symptom onset (20)

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