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Most adult heart surgery in Australia and New Zealand is performed for coronary artery disease and heart valve disease

10.1210/en.2012-1937 [DOI] [PubMed] [Google Scholar] 75.Drucker DJ

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However, I recommend not exceeding the doses prescribed by the manufacturer, to inform your treating physician before any dosage above 400 mg or when taking medication, and not to consume it for a period longer than 3 months without medical advice.