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Lys(9) for Glu(9) substitution in glucagon-like peptide-1(7-36)amide confers dipeptidylpeptidase IV resistance with cellular and metabolic actions similar to those of established antagonists glucagon-like peptide-1(936)amide and exendin (939)
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Total loss by week 24 typically ranges from 18-22% based on Phase 2 data
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Acta Pharmacol Sin (2012) 33:127784.10.1038/aps.2012.83 145 InamoriMTogawaJMatsumotoSHaradKMatsuuraMIidaHet alProtective effect of lactoferrin on acute acid reflux-induced esophageal mucosal damage
Several other GLP-1 receptor agonists are available in the UK, each with distinct characteristics regarding formulation, dosing frequency, and licensed indications
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