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At the molecular and cellular levels, the LNP system promoted cell proliferation and migration by enhancing the expression of proliferation markers (Ki-67 and proliferating cell nuclear antigen (PCNA)) and activating the phosphoinositide 3-kinase/protein kinase B (PI3K/AKT) and extracellular signal-regulated kinase (ERK) signaling pathways in keratinocytes (Fig

We can use that, and are using that, as an inroad into understanding the molecular basis of that vulnerability because ultimately glaucoma is a vulnerability to pressure, and not necessarily due to pressure level per se

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In the spine, arthritis can lead to stiffness, pain, and difficulty moving

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