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Indeed, in individuals with protein deprivation there is a significant impairment in urine concentrating and this can be restored by urea infusion (in experimental animals) or by restoration of protein intake in humans

This is an important treatment aspect, as weight reduction most likely plays an important role in the prevention and reduced progression of CKD, an association demonstrated in people with macroalbuminuria having undergone bariatric surgery [115]

The SURPASS clinical trials have highlighted its significant A1C lowering and weight loss benefits, marking it as a promising option for patients with diabetes and obesity

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This can be especially useful during activities, travel, or overnight usage, helping to manage movements confidently