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Excessive iron levels can generate produce ROS via the Fenton reaction, activating various intracellular signaling pathways that enhance bone absorption and inhibit bone formation, thereby contributing to osteoporosis

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This multitiered defence system comprises an endogenous antioxidant enzyme system (e.g., SOD/CAT/GPx) and small-molecule free radical scavengers such as vitamin C/E and -carotene, which are supported by trace elements such as selenium and zinc, collectively maintaining redox homeostasis [18]

Appendix The Peterson Center on Healthcare and KFF are partnering to monitor how well the U.S

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