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ClinicalTrialsgov (2021)

Detection and in vitro metabolism of AOD9604

Alternative diagnoses and diagnostic categories include, but are not limited to: Neuromuscular disorders (such as myopathic EDS and Bethlem myopathy) Other heritable connective tissue disorders (such as other types of EDS, LoeysDietz syndrome, Marfan syndrome) Skeletal dysplasias (such as osteogenesis imperfecta) HSD in Adults Adults are diagnosed with HSD if they have symptomatic joint hypermobility that cannot be explained by other conditions

TB-500 is commonly discussed for recovery, mobility, tissue support, and inflammation-related concerns

The Increlex (mecasermin) FDA label, which covers native rhIGF-1 in pediatric severe primary IGFD, is the closest human reference and informs the contraindications below