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PDE5 is an enzyme that is found in many parts of the body including in the smooth muscle of the corpus cavernosum, prostate, bladder, the vascular and visceral smooth muscle, skeletal muscle, urethra, platelets, kidney, lung, cerebellum, heart, liver, testis, seminal vesicle, and pancreas

doi: 10.1210/jcem.74.4.1532179 36 WiersingaWM

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In most cases, candida overgrowth in the gut develops as a result of excessive antibiotic use, as well as bad eating habits with a diet high in processed carbohydrates and sugars

It works best when combined with proper nutrition habits, regular physical activity, quality sleep, and overall healthy routines