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Permanently reduce Pemetrexed Injection in patients with an ANC of less than 500 cells/mm3 or platelet count of less than 50,000 cells/mm3 in previous cycles [see Dosage and Administration (2.6)]

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Citation: Chang, C

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[3] It is typically prescribed for people who cannot absorb biotin from food or supplements normally (for example, those with certain metabolic disorders or individuals on long-term intravenous feeding)