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10.1016/S0893-133X(00)00113-5 Neuropsychopharmacology 57 WhiteN

And the rebound question matters: research shows 60-163% of weight lost on GLP-1 agonists (conventional dosing) is regained after discontinuation, bringing its own hormonal recalibration that most prescribers are not preparing patients for

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Blood 96 , 11191124 (2000)

This was within the range reported by previous real-world studies: 2639% and 1672% of incident users received the 0.5 mg and 1.0 mg formulations, respectively, while 13% to 30% and 6788% of prevalent users received the 0.5 mg and 1.0 mg formulations, respectively [13, 20,21,22]