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Oral cimetidine gives effective symptom relief in painful bladder disease: a prospective, randomized, double-blind placebo-controlled trial

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Evidence from metabolism studies, case reports and larger systematic retrospective case reviews but no prospective controlled trials demonstrate that following single acute paracetamol overdose , children may be relatively protected from acute liver injury and hepatotoxicity when compared to adults [15, 46, 51,52,53, 58]

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10.21037/jtd-2025-1159 J Thorac Dis