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In certain instances, once exposure to an active agent (e.g., concentration in the endolymph or perilymph) reaches steady state, the concentration of an active agent in the endolymph or perilymph stays at or about the therapeutic dose for an extended period of time (e.g., one day, 2 days, 3 days, 4 days, 5 days, 6 days, 1 week, 3 weeks, 6 weeks, or 2 months)

Lets go back in time to the mid 1920s when the Nobel prize for medicines recipients had received the honour for discovering that patients with Pernicious Anaemia could be kept alive by giving them raw or slightly cooked liver

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