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Human Topical Evidence The most consumer-relevant tier of evidence actual clinical trials in humans is also the most variable
Dichloroacetate (DCA) can enhance metformin-induced oxidative damage with simultaneous reduce of metformin promoted lactate production through PDK1 inhibition, suggesting the innovative combinations, such as metformin and DCA, will be promising in expanding breast cancer therapies (302)
Analysis of CD8+ T cells from primary human head and neck squamous cell carcinomas, regional LNs and blood shows that the non-metastatic TDLNs are the source of pre-exhausted CD8+ T cells (Tpex), which migrate to the tumor (52)
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Arthritis Rheum 43(1):30-37
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