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The peptide induced expression of cytoskeleton proteins, intracellular kinases, and transcription regulators while repressing immune and inflammatory mediators, leading to down-regulation of oxidative stress response and up-regulation of ion channels and metabolic pathways

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In the trial, which enrolled 349 adults with type 2 diabetes and obesity, mazdutide showed greater improvements in both HbA1C - a measure of blood sugar over time - and weight reduction