Mitochondrial issues can be triggered by genetics with mutations in key genes that control metabolism, (MTHFR,MTRR, CBS, COMT), viral illness such as CMV, EBV viruses, toxin overload from heavy metals (lead, mercury, thalium, cadmium) and persistent organic pollutants (POP) including PCB, BPA, organophosphate pesticides, and others as well as nutrient deficiency relative to these other issues
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Mantle D, Hargreaves IP, Domingo JC, Castro-Marrero J
Biomaterials 223 , 119464 (2019)
Description "Use of acetyl L-carnitine in combination with propionyl L-carnitine and sildenqfilfor the treatment of erectile dysfunction" The present invention relates to the use of acetyl L-carnitine and sildenafil for the preparation of a medicament for the treatment of erectile dysfunction (ED) secondary to all those conditions in which there is distress or iatrogenic damage or trauma of the lesser pelvis within which the neurovascular bundles of the penis run