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Xia C, Diamond ML, Peaslee GF, et al

Tumor growth was monitored regularly, and tumor volume was calculated using the ellipsoid formula: V = ( L W 2 )/2, where L represents tumor length and W represents tumor width

showed that TMAO not only promoted cellular inflammation but also accounted for oxidative stress, thus playing an indirect role in promoting expression of inflammatory cytokines (74)

Its key advantages are prolonged sterility (multi-dose use) and slight anesthetic effect, but it must be used correctly: always dilute drugs per guidelines, ensure the final solution is isotonic, and heed contraindications (no neonates, no intrathecal use)

Cells adjacent to the wound formed a migrating front with reduced proliferation and stratification with a surrounding area of highly proliferative cells, reproducing changes seen following excisional wounding of the esophagus in vivo (Fig